Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sigK_2ECF RNA polymerase sigma factor SigK; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa)    
Predicted Functional Partners:
T45_03521
anti-sigma-K factor RskA.
 
 
 0.906
rskA
anti-sigma-K factor RskA.
 
 
 0.888
T45_02129
Hypothetical protein.
       0.873
rpoB_1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.598
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.561
sigL_1
ECF RNA polymerase sigma factor SigL; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.532
T45_02128
Sporulation inhibitor KapD.
       0.528
rsbV_3
anti-sigma-B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
    0.525
T45_02132
Calerythrin.
       0.519
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.515
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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