close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sttH_1Streptothricin hydrolase. (174 aa)    
Predicted Functional Partners:
nicF_2
Maleamate amidohydrolase.
  
  
  0.864
accA1_1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain.
    
  0.820
vgb_2
Virginiamycin B lyase.
  
 
  0.682
nicF_1
Maleamate amidohydrolase.
  
  
  0.667
dhbF_8
Dimodular nonribosomal peptide synthase.
  
 
 0.536
ttgW_3
Putative HTH-type transcriptional regulator.
       0.516
nnr
Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...]
  
    0.475
nadB_2
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
   
 0.451
pncB1
Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.427
morA
Morphine 6-dehydrogenase.
  
 
  0.410
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (32%) [HD]