mqnE_1 protein (Streptomyces turgidiscabies)

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Score

mqnE_1

Aminodeoxyfutalosine synthase. (870 aa)

Predicted Functional Partners:

cofD

0.990

thiG

0.956

mqnD

0.923

mqnB

0.903

T45_02234

0.871

thiS

0.845

thiC

0.844

rsbU_4

0.837

rsbU_7

0.837

rsbP_4

0.837

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_02234	cofD	T45_02234	T45_08636	Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.	2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.	0.489
T45_02234	mqnE_1	T45_02234	T45_02235	Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.	Aminodeoxyfutalosine synthase.	0.871
cofD	T45_02234	T45_08636	T45_02234	2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.	Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.	0.489
cofD	mqnE_1	T45_08636	T45_02235	2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.	Aminodeoxyfutalosine synthase.	0.990
mqnB	mqnD	T45_06148	T45_06147	Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).	1,4-dihydroxy-6-naphtoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.	0.995
mqnB	mqnE_1	T45_06148	T45_02235	Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).	Aminodeoxyfutalosine synthase.	0.903
mqnD	mqnB	T45_06147	T45_06148	1,4-dihydroxy-6-naphtoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.	Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).	0.995
mqnD	mqnE_1	T45_06147	T45_02235	1,4-dihydroxy-6-naphtoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.	Aminodeoxyfutalosine synthase.	0.923
mqnE_1	T45_02234	T45_02235	T45_02234	Aminodeoxyfutalosine synthase.	Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.	0.871
mqnE_1	cofD	T45_02235	T45_08636	Aminodeoxyfutalosine synthase.	2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.	0.990
mqnE_1	mqnB	T45_02235	T45_06148	Aminodeoxyfutalosine synthase.	Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).	0.903
mqnE_1	mqnD	T45_02235	T45_06147	Aminodeoxyfutalosine synthase.	1,4-dihydroxy-6-naphtoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.	0.923
mqnE_1	rsbP_4	T45_02235	T45_03804	Aminodeoxyfutalosine synthase.	Phosphoserine phosphatase RsbP.	0.837
mqnE_1	rsbU_4	T45_02235	T45_02824	Aminodeoxyfutalosine synthase.	Phosphoserine phosphatase RsbU.	0.837
mqnE_1	rsbU_7	T45_02235	T45_03649	Aminodeoxyfutalosine synthase.	Phosphoserine phosphatase RsbU.	0.837
mqnE_1	thiC	T45_02235	T45_01339	Aminodeoxyfutalosine synthase.	Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	0.844
mqnE_1	thiG	T45_02235	T45_03957	Aminodeoxyfutalosine synthase.	Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.956
mqnE_1	thiS	T45_02235	T45_03958	Aminodeoxyfutalosine synthase.	Sulfur carrier protein ThiS.	0.845
rsbP_4	mqnE_1	T45_03804	T45_02235	Phosphoserine phosphatase RsbP.	Aminodeoxyfutalosine synthase.	0.837
rsbP_4	rsbU_4	T45_03804	T45_02824	Phosphoserine phosphatase RsbP.	Phosphoserine phosphatase RsbU.	0.904