Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
gpx2Hydroperoxy fatty acid reductase gpx2; Belongs to the glutathione peroxidase family. (175 aa)    
Predicted Functional Partners:
ggt
Gamma-glutamyltranspeptidase precursor.
     
 0.876
ywrD
Putative gamma-glutamyltransferase YwrD.
     
 0.876
T45_02257
Helix-turn-helix domain protein.
       0.873
sodF1
Superoxide dismutase [Fe-Zn] 1; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.866
msrA3
Peptide methionine sulfoxide reductase MsrA 3; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.781
resA
Thiol-disulfide oxidoreductase ResA.
   
 0.768
trxA_5
Thioredoxin.
   
 0.768
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 
 0.717
katA
Catalase.
  
 
 0.717
gap2_2
Glyceraldehyde-3-phosphate dehydrogenase 2.
   
 
 0.689
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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