Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fruAPTS system fructose-specific EIIABC component. (692 aa)    
Predicted Functional Partners:
lacC_1
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
lacC_2
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.999
ptsH
Phosphocarrier protein HPr.
 
 
 0.998
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.998
crr
Glucose-specific phosphotransferase enzyme IIA.
 
 
 0.993
manA_2
Mannose-6-phosphate isomerase.
  
 
 0.993
srlR_2
Glucitol operon repressor.
 
  
 0.990
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.967
fbaA
Putative fructose-bisphosphate aldolase.
  
 
 0.966
kbaY
D-tagatose-1,6-bisphosphate aldolase subunit.
  
 
 0.966
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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