nhaP protein (Streptomyces turgidiscabies) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

nhaP

K(+)/ H(+) antiporter NhaP. (547 aa)

Predicted Functional Partners:

quiP

0.760

T45_02399

0.708

mscL

0.580

ask

0.544

mtnP

0.525

metH

0.403

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_02399	metH	T45_02399	T45_03400	Enterobactin exporter EntS.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.484
T45_02399	mscL	T45_02399	T45_02395	Enterobactin exporter EntS.	Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	0.524
T45_02399	mtnP	T45_02399	T45_02397	Enterobactin exporter EntS.	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	0.520
T45_02399	nhaP	T45_02399	T45_02400	Enterobactin exporter EntS.	K(+)/ H(+) antiporter NhaP.	0.708
T45_02399	quiP	T45_02399	T45_02401	Enterobactin exporter EntS.	Acyl-homoserine lactone acylase QuiP precursor.	0.654
ask	metH	T45_00859	T45_03400	Aspartokinase; Belongs to the aspartokinase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.964
ask	nhaP	T45_00859	T45_02400	Aspartokinase; Belongs to the aspartokinase family.	K(+)/ H(+) antiporter NhaP.	0.544
metH	T45_02399	T45_03400	T45_02399	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Enterobactin exporter EntS.	0.484
metH	ask	T45_03400	T45_00859	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Aspartokinase; Belongs to the aspartokinase family.	0.964
metH	nhaP	T45_03400	T45_02400	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	K(+)/ H(+) antiporter NhaP.	0.403
mscL	T45_02399	T45_02395	T45_02399	Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	Enterobactin exporter EntS.	0.524
mscL	mtnP	T45_02395	T45_02397	Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	0.653
mscL	nhaP	T45_02395	T45_02400	Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	K(+)/ H(+) antiporter NhaP.	0.580
mtnP	T45_02399	T45_02397	T45_02399	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	Enterobactin exporter EntS.	0.520
mtnP	mscL	T45_02397	T45_02395	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.	0.653
mtnP	nhaP	T45_02397	T45_02400	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	K(+)/ H(+) antiporter NhaP.	0.525
mtnP	quiP	T45_02397	T45_02401	S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.	Acyl-homoserine lactone acylase QuiP precursor.	0.519
nhaP	T45_02399	T45_02400	T45_02399	K(+)/ H(+) antiporter NhaP.	Enterobactin exporter EntS.	0.708
nhaP	ask	T45_02400	T45_00859	K(+)/ H(+) antiporter NhaP.	Aspartokinase; Belongs to the aspartokinase family.	0.544
nhaP	metH	T45_02400	T45_03400	K(+)/ H(+) antiporter NhaP.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.403