T45_02431 protein (Streptomyces turgidiscabies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

T45_02431

Calcineurin-like phosphoesterase. (489 aa)

Predicted Functional Partners:

barA_2

0.924

luxQ

0.880

T45_09072

0.848

T45_01573

0.838

yhcR

0.836

adoK

0.834

yjjG

0.824

cpdA_2

0.817

apt_2

0.800

cpdA_1

0.789

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_01573	T45_02431	T45_01573	T45_02431	PH-sensitive adenylate cyclase.	Calcineurin-like phosphoesterase.	0.838
T45_01573	T45_09072	T45_01573	T45_09072	PH-sensitive adenylate cyclase.	Sensory histidine kinase AtoS.	0.941
T45_01573	barA_2	T45_01573	T45_05328	PH-sensitive adenylate cyclase.	Signal transduction histidine-protein kinase.	0.985
T45_01573	cpdA_1	T45_01573	T45_00082	PH-sensitive adenylate cyclase.	3',5'-cyclic adenosine monophosphate.	0.854
T45_01573	cpdA_2	T45_01573	T45_02697	PH-sensitive adenylate cyclase.	3',5'-cyclic adenosine monophosphate; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.	0.854
T45_01573	luxQ	T45_01573	T45_00537	PH-sensitive adenylate cyclase.	Autoinducer 2 sensor kinase/phosphatase LuxQ.	0.974
T45_02431	T45_01573	T45_02431	T45_01573	Calcineurin-like phosphoesterase.	PH-sensitive adenylate cyclase.	0.838
T45_02431	T45_09072	T45_02431	T45_09072	Calcineurin-like phosphoesterase.	Sensory histidine kinase AtoS.	0.848
T45_02431	adoK	T45_02431	T45_03911	Calcineurin-like phosphoesterase.	Adenosine kinase.	0.834
T45_02431	apt_2	T45_02431	T45_08408	Calcineurin-like phosphoesterase.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.800
T45_02431	barA_2	T45_02431	T45_05328	Calcineurin-like phosphoesterase.	Signal transduction histidine-protein kinase.	0.924
T45_02431	cpdA_1	T45_02431	T45_00082	Calcineurin-like phosphoesterase.	3',5'-cyclic adenosine monophosphate.	0.789
T45_02431	cpdA_2	T45_02431	T45_02697	Calcineurin-like phosphoesterase.	3',5'-cyclic adenosine monophosphate; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.	0.817
T45_02431	luxQ	T45_02431	T45_00537	Calcineurin-like phosphoesterase.	Autoinducer 2 sensor kinase/phosphatase LuxQ.	0.880
T45_02431	yhcR	T45_02431	T45_05991	Calcineurin-like phosphoesterase.	Endonuclease YhcR precursor; Belongs to the 5'-nucleotidase family.	0.836
T45_02431	yjjG	T45_02431	T45_05831	Calcineurin-like phosphoesterase.	Pyrimidine 5'-nucleotidase YjjG.	0.824
T45_09072	T45_01573	T45_09072	T45_01573	Sensory histidine kinase AtoS.	PH-sensitive adenylate cyclase.	0.941
T45_09072	T45_02431	T45_09072	T45_02431	Sensory histidine kinase AtoS.	Calcineurin-like phosphoesterase.	0.848
T45_09072	barA_2	T45_09072	T45_05328	Sensory histidine kinase AtoS.	Signal transduction histidine-protein kinase.	0.999
T45_09072	cpdA_1	T45_09072	T45_00082	Sensory histidine kinase AtoS.	3',5'-cyclic adenosine monophosphate.	0.848