mazG protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

mazG

Nucleoside triphosphate pyrophosphohydrolase. (369 aa)

Predicted Functional Partners:

luxQ

0.951

barA_2

0.947

rdgB

0.911

hpt

0.902

guaA_2

0.896

T45_00337

0.893

yhcR

0.893

guaB_6

0.892

cmk

0.878

relA_2

0.875

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_00337	guaA_2	T45_00337	T45_07354	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.907
T45_00337	guaB_6	T45_00337	T45_08195	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	Inosine-5'-monophosphate dehydrogenase.	0.905
T45_00337	hpt	T45_00337	T45_07524	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.931
T45_00337	mazG	T45_00337	T45_02504	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	Nucleoside triphosphate pyrophosphohydrolase.	0.893
T45_00337	rdgB	T45_00337	T45_04305	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	DITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.891
T45_00337	yhcR	T45_00337	T45_05991	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	Endonuclease YhcR precursor; Belongs to the 5'-nucleotidase family.	0.921
barA_2	guaA_2	T45_05328	T45_07354	Signal transduction histidine-protein kinase.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.720
barA_2	guaB_6	T45_05328	T45_08195	Signal transduction histidine-protein kinase.	Inosine-5'-monophosphate dehydrogenase.	0.575
barA_2	hpt	T45_05328	T45_07524	Signal transduction histidine-protein kinase.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.681
barA_2	luxQ	T45_05328	T45_00537	Signal transduction histidine-protein kinase.	Autoinducer 2 sensor kinase/phosphatase LuxQ.	0.999
barA_2	mazG	T45_05328	T45_02504	Signal transduction histidine-protein kinase.	Nucleoside triphosphate pyrophosphohydrolase.	0.947
barA_2	relA_2	T45_05328	T45_08409	Signal transduction histidine-protein kinase.	Bifunctional (p)ppGpp synthase/hydrolase relA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.968
cmk	guaA_2	T45_03567	T45_07354	Cytidylate kinase.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.575
cmk	guaB_6	T45_03567	T45_08195	Cytidylate kinase.	Inosine-5'-monophosphate dehydrogenase.	0.417
cmk	mazG	T45_03567	T45_02504	Cytidylate kinase.	Nucleoside triphosphate pyrophosphohydrolase.	0.878
guaA_2	T45_00337	T45_07354	T45_00337	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein.	0.907
guaA_2	barA_2	T45_07354	T45_05328	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Signal transduction histidine-protein kinase.	0.720
guaA_2	cmk	T45_07354	T45_03567	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Cytidylate kinase.	0.575
guaA_2	guaB_6	T45_07354	T45_08195	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase.	0.999
guaA_2	hpt	T45_07354	T45_07524	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.969