cbs_1 protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

cbs_1

Putative cystathionine beta-synthase. (462 aa)

Predicted Functional Partners:

metB_2

0.992

metB_1

0.986

metH

0.919

narB_2

0.916

serB

0.895

serA_3

0.892

sir

0.891

ahcY

0.871

guaA_2

0.860

guaB_5

0.857

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ahcY	cbs_1	T45_08648	T45_02526	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Putative cystathionine beta-synthase.	0.871
ahcY	guaA_2	T45_08648	T45_07354	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.433
ahcY	guaB_5	T45_08648	T45_07370	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.556
ahcY	metB_1	T45_08648	T45_01330	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Cystathionine gamma-synthase.	0.899
ahcY	metB_2	T45_08648	T45_01594	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Cystathionine gamma-synthase.	0.899
ahcY	metH	T45_08648	T45_03400	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.982
ahcY	serB	T45_08648	T45_07949	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	Phosphoserine phosphatase.	0.491
cbs_1	ahcY	T45_02526	T45_08648	Putative cystathionine beta-synthase.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.871
cbs_1	guaA_2	T45_02526	T45_07354	Putative cystathionine beta-synthase.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.860
cbs_1	guaB_5	T45_02526	T45_07370	Putative cystathionine beta-synthase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.857
cbs_1	metB_1	T45_02526	T45_01330	Putative cystathionine beta-synthase.	Cystathionine gamma-synthase.	0.986
cbs_1	metB_2	T45_02526	T45_01594	Putative cystathionine beta-synthase.	Cystathionine gamma-synthase.	0.992
cbs_1	metH	T45_02526	T45_03400	Putative cystathionine beta-synthase.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.919
cbs_1	narB_2	T45_02526	T45_05524	Putative cystathionine beta-synthase.	Nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.916
cbs_1	serA_3	T45_02526	T45_05874	Putative cystathionine beta-synthase.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.892
cbs_1	serB	T45_02526	T45_07949	Putative cystathionine beta-synthase.	Phosphoserine phosphatase.	0.895
cbs_1	sir	T45_02526	T45_02661	Putative cystathionine beta-synthase.	Sulfite reductase [ferredoxin]; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.891
guaA_2	ahcY	T45_07354	T45_08648	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.433
guaA_2	cbs_1	T45_07354	T45_02526	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Putative cystathionine beta-synthase.	0.860
guaA_2	guaB_5	T45_07354	T45_07370	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999