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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbuG_1Guanine/hypoxanthine permease PbuG. (478 aa)    
Predicted Functional Partners:
vgb_2
Virginiamycin B lyase.
     
 0.732
cutS_1
Carbon monoxide dehydrogenase small chain.
       0.725
ndhF
Nicotinate dehydrogenase FAD-subunit.
       0.725
pucA_1
Putative xanthine dehydrogenase subunit A.
       0.657
T45_02571
Carbohydrate diacid transcriptional activator.
       0.656
T45_02572
Hypothetical protein.
       0.550
ghrB_3
Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.528
uacT
Uric acid transporter UacT.
 
  
 0.516
purL
Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
  
 0.515
pucD_1
Putative xanthine dehydrogenase subunit D.
       0.510
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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