Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_02662Hypothetical protein. (62 aa)    
Predicted Functional Partners:
sir
Sulfite reductase [ferredoxin]; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.980
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
  
 0.979
cysD
Sulfate adenylyltransferase subunit 2.
  
  
 0.919
cysNC
Bifunctional enzyme CysN/CysC; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.909
cbiX_2
Sirohydrochlorin cobaltochelatase.
     
 0.815
fprA_1
NADPH-ferredoxin reductase FprA.
  
  
 0.806
fprA_2
NADPH-ferredoxin reductase FprA.
  
  
 0.806
sat/cysC_1
Putative bifunctional SAT/APS kinase; Catalyzes the synthesis of activated sulfate.
       0.805
T45_02667
Hypothetical protein.
       0.798
ssuA_3
Putative aliphatic sulfonates-binding protein precursor.
       0.745
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (32%) [HD]