| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| T45_00337 | adk | T45_00337 | T45_04390 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.850 |
| T45_00337 | adoK | T45_00337 | T45_03911 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Adenosine kinase. | 0.850 |
| T45_00337 | apt_1 | T45_00337 | T45_06526 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Adenine phosphoribosyltransferase. | 0.781 |
| T45_00337 | apt_2 | T45_00337 | T45_08408 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.867 |
| T45_00337 | cpdA_2 | T45_00337 | T45_02697 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | 3',5'-cyclic adenosine monophosphate; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.763 |
| T45_00337 | guaA_2 | T45_00337 | T45_07354 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.864 |
| T45_00337 | nagD | T45_00337 | T45_04235 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Ribonucleotide monophosphatase NagD; Belongs to the HAD-like hydrolase superfamily. | 0.872 |
| T45_00337 | purB | T45_00337 | T45_03020 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.859 |
| T45_00337 | yhcR | T45_00337 | T45_05991 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | Endonuclease YhcR precursor; Belongs to the 5'-nucleotidase family. | 0.892 |
| T45_02431 | adk | T45_02431 | T45_04390 | Calcineurin-like phosphoesterase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.772 |
| T45_02431 | adoK | T45_02431 | T45_03911 | Calcineurin-like phosphoesterase. | Adenosine kinase. | 0.772 |
| T45_02431 | apt_1 | T45_02431 | T45_06526 | Calcineurin-like phosphoesterase. | Adenine phosphoribosyltransferase. | 0.719 |
| T45_02431 | apt_2 | T45_02431 | T45_08408 | Calcineurin-like phosphoesterase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.746 |
| T45_02431 | cpdA_2 | T45_02431 | T45_02697 | Calcineurin-like phosphoesterase. | 3',5'-cyclic adenosine monophosphate; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.779 |
| T45_02431 | guaA_2 | T45_02431 | T45_07354 | Calcineurin-like phosphoesterase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.724 |
| T45_02431 | nagD | T45_02431 | T45_04235 | Calcineurin-like phosphoesterase. | Ribonucleotide monophosphatase NagD; Belongs to the HAD-like hydrolase superfamily. | 0.772 |
| T45_02431 | purB | T45_02431 | T45_03020 | Calcineurin-like phosphoesterase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.772 |
| T45_02431 | yhcR | T45_02431 | T45_05991 | Calcineurin-like phosphoesterase. | Endonuclease YhcR precursor; Belongs to the 5'-nucleotidase family. | 0.773 |
| adk | T45_00337 | T45_04390 | T45_00337 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor protein. | 0.850 |
| adk | T45_02431 | T45_04390 | T45_02431 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Calcineurin-like phosphoesterase. | 0.772 |