ywtF_2 protein (Streptomyces turgidiscabies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ywtF_2

Putative transcriptional regulator YwtF. (361 aa)

Predicted Functional Partners:

dhbF_8

0.705

yvhJ_3

0.634

brpA

0.598

lgrD_2

0.506

sepF_2

0.488

T45_01293

0.483

thrB

0.466

lrtA

0.454

lgrB

0.443

T45_04143

0.443

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_01293	brpA	T45_01293	T45_07870	R3H domain protein.	Biofilm regulatory protein A precursor.	0.480
T45_01293	lrtA	T45_01293	T45_09312	R3H domain protein.	Light-repressed protein A; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.	0.409
T45_01293	yvhJ_3	T45_01293	T45_08625	R3H domain protein.	Putative transcriptional regulator YvhJ.	0.516
T45_01293	ywtF_2	T45_01293	T45_02785	R3H domain protein.	Putative transcriptional regulator YwtF.	0.483
T45_04143	brpA	T45_04143	T45_07870	Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.	Biofilm regulatory protein A precursor.	0.583
T45_04143	thrB	T45_04143	T45_02012	Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.422
T45_04143	yvhJ_3	T45_04143	T45_08625	Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.	Putative transcriptional regulator YvhJ.	0.435
T45_04143	ywtF_2	T45_04143	T45_02785	Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.	Putative transcriptional regulator YwtF.	0.443
brpA	T45_01293	T45_07870	T45_01293	Biofilm regulatory protein A precursor.	R3H domain protein.	0.480
brpA	T45_04143	T45_07870	T45_04143	Biofilm regulatory protein A precursor.	Putative gluconeogenesis factor; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.	0.583
brpA	dhbF_8	T45_07870	T45_05484	Biofilm regulatory protein A precursor.	Dimodular nonribosomal peptide synthase.	0.705
brpA	lgrB	T45_07870	T45_02352	Biofilm regulatory protein A precursor.	Linear gramicidin synthase subunit B.	0.443
brpA	lgrD_2	T45_07870	T45_05481	Biofilm regulatory protein A precursor.	Linear gramicidin synthase subunit D.	0.506
brpA	lrtA	T45_07870	T45_09312	Biofilm regulatory protein A precursor.	Light-repressed protein A; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.	0.541
brpA	sepF_2	T45_07870	T45_03992	Biofilm regulatory protein A precursor.	Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.	0.585
brpA	thrB	T45_07870	T45_02012	Biofilm regulatory protein A precursor.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.476
brpA	ywtF_2	T45_07870	T45_02785	Biofilm regulatory protein A precursor.	Putative transcriptional regulator YwtF.	0.598
dhbF_8	brpA	T45_05484	T45_07870	Dimodular nonribosomal peptide synthase.	Biofilm regulatory protein A precursor.	0.705
dhbF_8	lgrB	T45_05484	T45_02352	Dimodular nonribosomal peptide synthase.	Linear gramicidin synthase subunit B.	0.999
dhbF_8	lgrD_2	T45_05484	T45_05481	Dimodular nonribosomal peptide synthase.	Linear gramicidin synthase subunit D.	0.999