Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tcrX_3Putative transcriptional regulatory protein. (152 aa)    
Predicted Functional Partners:
barA_2
Signal transduction histidine-protein kinase.
  
 0.985
luxQ
Autoinducer 2 sensor kinase/phosphatase LuxQ.
  
 0.958
T45_09072
Sensory histidine kinase AtoS.
  
 0.936
tcrY_2
Putative sensor histidine kinase TcrY.
 
  0.887
T45_01411
Sensory histidine kinase AtoS.
  
 0.730
rsbU_3
Phosphoserine phosphatase RsbU.
   
 0.678
T45_07062
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 0.678
hemD_2
Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein.
     
 0.619
gmr_2
Cyclic di-GMP phosphodiesterase Gmr.
  
 0.612
rpoB_1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.600
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (18%) [HD]