guaB_1 protein (Streptomyces turgidiscabies)

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Score

guaB_1

Inosine-5'-monophosphate dehydrogenase. (236 aa)

Predicted Functional Partners:

guaA_2

0.965

guaB_5

0.759

guaB_4

0.741

metH

0.666

guaA_1

0.562

T45_02837

0.506

purA

0.493

atpC

0.477

acuC

0.477

atpE

0.466

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_02837	guaB_1	T45_02837	T45_02838	Hypothetical protein.	Inosine-5'-monophosphate dehydrogenase.	0.506
acuC	guaB_1	T45_06550	T45_02838	Acetoin utilization protein AcuC.	Inosine-5'-monophosphate dehydrogenase.	0.477
atpC	atpE	T45_02031	T45_02025	ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	0.999
atpC	guaB_1	T45_02031	T45_02838	ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Inosine-5'-monophosphate dehydrogenase.	0.477
atpC	guaB_4	T45_02031	T45_06939	ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Inosine-5'-monophosphate dehydrogenase.	0.597
atpC	guaB_5	T45_02031	T45_07370	ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.659
atpE	atpC	T45_02025	T45_02031	ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
atpE	guaB_1	T45_02025	T45_02838	ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	Inosine-5'-monophosphate dehydrogenase.	0.466
atpE	guaB_4	T45_02025	T45_06939	ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	Inosine-5'-monophosphate dehydrogenase.	0.626
atpE	guaB_5	T45_02025	T45_07370	ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.649
guaA_1	guaA_2	T45_00203	T45_07354	GMP synthase [glutamine-hydrolyzing].	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.912
guaA_1	guaB_1	T45_00203	T45_02838	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase.	0.562
guaA_1	guaB_4	T45_00203	T45_06939	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase.	0.918
guaA_1	guaB_5	T45_00203	T45_07370	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.990
guaA_1	purA	T45_00203	T45_00906	GMP synthase [glutamine-hydrolyzing].	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.614
guaA_2	guaA_1	T45_07354	T45_00203	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	GMP synthase [glutamine-hydrolyzing].	0.912
guaA_2	guaB_1	T45_07354	T45_02838	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase.	0.965
guaA_2	guaB_4	T45_07354	T45_06939	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase.	0.999
guaA_2	guaB_5	T45_07354	T45_07370	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA_2	metH	T45_07354	T45_03400	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.725