T45_02888 protein (Streptomyces turgidiscabies)

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T45_02888

Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa)

Predicted Functional Partners:

T45_02887

0.970

nadE

0.870

arcA

0.739

T45_05411

0.715

argF_1

0.679

T45_03576

0.641

nadD

0.630

tlyA

0.590

coaD

0.582

rsfS

0.564

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_02887	T45_02888	T45_02887	T45_02888	SPFH domain / Band 7 family protein.	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.970
T45_02887	T45_03576	T45_02887	T45_03576	SPFH domain / Band 7 family protein.	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	0.516
T45_02887	T45_05411	T45_02887	T45_05411	SPFH domain / Band 7 family protein.	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	0.618
T45_02887	arcA	T45_02887	T45_02886	SPFH domain / Band 7 family protein.	Arginine deiminase.	0.743
T45_02887	argF_1	T45_02887	T45_02885	SPFH domain / Band 7 family protein.	Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.	0.668
T45_02888	T45_02887	T45_02888	T45_02887	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	SPFH domain / Band 7 family protein.	0.970
T45_02888	T45_03576	T45_02888	T45_03576	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	0.641
T45_02888	T45_05411	T45_02888	T45_05411	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	0.715
T45_02888	arcA	T45_02888	T45_02886	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Arginine deiminase.	0.739
T45_02888	argF_1	T45_02888	T45_02885	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.	0.679
T45_02888	coaD	T45_02888	T45_05803	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	0.582
T45_02888	nadD	T45_02888	T45_00558	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.630
T45_02888	nadE	T45_02888	T45_06531	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Glutamine-dependent NAD(+)synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.870
T45_02888	rsfS	T45_02888	T45_00556	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.564
T45_02888	tlyA	T45_02888	T45_03592	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	16S/23S rRNA (cytidine-2'-O-methyltransferase.	0.590
T45_03576	T45_02887	T45_03576	T45_02887	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	SPFH domain / Band 7 family protein.	0.516
T45_03576	T45_02888	T45_03576	T45_02888	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.641
T45_03576	nadD	T45_03576	T45_00558	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.423
T45_03576	nadE	T45_03576	T45_06531	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	Glutamine-dependent NAD(+)synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.823
T45_05411	T45_02887	T45_05411	T45_02887	Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family.	SPFH domain / Band 7 family protein.	0.618

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