purB protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

purB

Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)

Predicted Functional Partners:

purA

0.998

purH

0.996

purC

0.996

purD_1

0.982

adk

0.978

purN

0.972

apt_2

0.969

purF

0.957

purE

0.953

apt_1

0.946

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adk	apt_1	T45_04390	T45_06526	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenine phosphoribosyltransferase.	0.883
adk	apt_2	T45_04390	T45_08408	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.932
adk	purA	T45_04390	T45_00906	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.847
adk	purB	T45_04390	T45_03020	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.978
adk	purH	T45_04390	T45_01442	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	Bifunctional purine biosynthesis protein PurH; Belongs to the PurH family.	0.650
apt_1	adk	T45_06526	T45_04390	Adenine phosphoribosyltransferase.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.883
apt_1	apt_2	T45_06526	T45_08408	Adenine phosphoribosyltransferase.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.849
apt_1	purA	T45_06526	T45_00906	Adenine phosphoribosyltransferase.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.748
apt_1	purB	T45_06526	T45_03020	Adenine phosphoribosyltransferase.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.946
apt_1	purC	T45_06526	T45_08889	Adenine phosphoribosyltransferase.	Phosphoribosylaminoimidazole-succinocarboxamide; Belongs to the SAICAR synthetase family.	0.426
apt_1	purD_1	T45_06526	T45_08892	Adenine phosphoribosyltransferase.	Phosphoribosylamine--glycine ligase; Belongs to the GARS family.	0.495
apt_1	purE	T45_06526	T45_08615	Adenine phosphoribosyltransferase.	N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.469
apt_1	purF	T45_06526	T45_08704	Adenine phosphoribosyltransferase.	Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.415
apt_1	purH	T45_06526	T45_01442	Adenine phosphoribosyltransferase.	Bifunctional purine biosynthesis protein PurH; Belongs to the PurH family.	0.922
apt_1	purN	T45_06526	T45_01441	Adenine phosphoribosyltransferase.	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.	0.709
apt_2	adk	T45_08408	T45_04390	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.	0.932
apt_2	apt_1	T45_08408	T45_06526	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenine phosphoribosyltransferase.	0.849
apt_2	purA	T45_08408	T45_00906	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.748
apt_2	purB	T45_08408	T45_03020	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.969
apt_2	purC	T45_08408	T45_08889	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Phosphoribosylaminoimidazole-succinocarboxamide; Belongs to the SAICAR synthetase family.	0.426