Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tfdB_12,4-dichlorophenol 6-monooxygenase. (553 aa)    
Predicted Functional Partners:
tcmI_1
Tetracenomycin polyketide synthesis protein.
 
  
  0.640
T45_03029
Hypothetical protein.
 
     0.594
tcmN_1
Multifunctional cyclase-dehydratase-3-O-methyl transferase.
  
  
  0.587
ubiE_9
Demethylmenaquinone methyltransferase.
 
 
 0.577
pcaH
Protocatechuate 3,4-dioxygenase beta chain.
 
 
 0.576
T45_03028
SchA/CurD like domain protein.
     
 0.564
puuB_1
Gamma-glutamylputrescine oxidoreductase.
   
 
 0.563
npcC
Hydroxyquinol 1,2-dioxygenase.
 
  
 0.550
T45_03033
Putative polyketide cyclase.
 
     0.549
bphC_1
Manganese-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase.
    
 0.547
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (30%) [HD]