Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_03032Actinorhodin polyketide synthase acyl carrier. (86 aa)    
Predicted Functional Partners:
dhbF_8
Dimodular nonribosomal peptide synthase.
  
 0.965
pksN
Polyketide synthase PksN; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.945
cmdD_1
Chondramide synthase cmdD.
  
 
 0.924
T45_03030
Actinorhodin polyketide putative beta-ketoacyl; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  0.889
T45_03031
Actinorhodin polyketide putative beta-ketoacyl; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  0.889
pks2
Phthioceranic/hydroxyphthioceranic acid.
  
 0.888
T45_03033
Putative polyketide cyclase.
       0.873
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 0.839
fabD
Malonyl CoA-acyl carrier protein transacylase.
  
 0.837
T45_03029
Hypothetical protein.
       0.833
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (10%) [HD]