T45_03043 protein (Streptomyces turgidiscabies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

T45_03043

Hypothetical protein. (239 aa)

Predicted Functional Partners:

dhbF_8

0.832

estB_2

0.752

mlr_1

0.740

bioD

0.637

lgrD_2

0.632

bioB

0.614

bioF1

0.610

lgrB

0.607

txtB

0.607

txtA

0.607

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_03043	bioB	T45_03043	T45_03048	Hypothetical protein.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.614
T45_03043	bioD	T45_03043	T45_03046	Hypothetical protein.	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.637
T45_03043	bioF1	T45_03043	T45_03049	Hypothetical protein.	8-amino-7-oxononanoate synthase 1.	0.610
T45_03043	dhbF_8	T45_03043	T45_05484	Hypothetical protein.	Dimodular nonribosomal peptide synthase.	0.832
T45_03043	estB_2	T45_03043	T45_03044	Hypothetical protein.	Extracellular esterase EstB precursor.	0.752
T45_03043	lgrB	T45_03043	T45_02352	Hypothetical protein.	Linear gramicidin synthase subunit B.	0.607
T45_03043	lgrD_2	T45_03043	T45_05481	Hypothetical protein.	Linear gramicidin synthase subunit D.	0.632
T45_03043	mlr_1	T45_03043	T45_00712	Hypothetical protein.	4-methylaminobutanoate oxidase; Belongs to the GcvT family.	0.740
T45_03043	txtA	T45_03043	T45_09185	Hypothetical protein.	Thaxtomin synthase A.	0.607
T45_03043	txtB	T45_03043	T45_09184	Hypothetical protein.	Thaxtomin synthase B.	0.607
bioB	T45_03043	T45_03048	T45_03043	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Hypothetical protein.	0.614
bioB	bioD	T45_03048	T45_03046	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.999
bioB	bioF1	T45_03048	T45_03049	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	8-amino-7-oxononanoate synthase 1.	0.970
bioD	T45_03043	T45_03046	T45_03043	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Hypothetical protein.	0.637
bioD	bioB	T45_03046	T45_03048	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.999
bioD	bioF1	T45_03046	T45_03049	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	8-amino-7-oxononanoate synthase 1.	0.993
bioD	txtA	T45_03046	T45_09185	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Thaxtomin synthase A.	0.437
bioD	txtB	T45_03046	T45_09184	ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	Thaxtomin synthase B.	0.437
bioF1	T45_03043	T45_03049	T45_03043	8-amino-7-oxononanoate synthase 1.	Hypothetical protein.	0.610
bioF1	bioB	T45_03049	T45_03048	8-amino-7-oxononanoate synthase 1.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.970