Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxB_2Thioredoxin reductase. (319 aa)    
Predicted Functional Partners:
trxC
Putative thioredoxin-2; Belongs to the thioredoxin family.
  
 0.926
gltB_1
Glutamate synthase [NADPH] large chain.
    
 0.852
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.845
puuR_2
HTH-type transcriptional regulator PuuR.
 
     0.843
resA
Thiol-disulfide oxidoreductase ResA.
   
 0.824
trxA_5
Thioredoxin.
   
 0.824
barA_2
Signal transduction histidine-protein kinase.
  
 
 0.804
T45_08491
NADH oxidase.
  
 0.792
T45_01767
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.789
trxB_1
Thioredoxin reductase.
     
  0.772
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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