Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_03193Nitrilase. (304 aa)    
Predicted Functional Partners:
nadB_2
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.893
gltB_1
Glutamate synthase [NADPH] large chain.
    
 0.892
gdhA
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.885
gltB_2
Glutamate synthase [NADPH] small chain.
 
  0.873
aldA
Putative aldehyde dehydrogenase AldA.
    
  0.865
gltB_3
Glutamate synthase [NADPH] small chain.
 
  0.864
rocA1
1-pyrroline-5-carboxylate dehydrogenase 1.
    
  0.864
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.863
hpd
4-hydroxyphenylpyruvate dioxygenase.
   
 0.860
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.856
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (30%) [HD]