Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cytR_2HTH-type transcriptional repressor CytR. (339 aa)    
Predicted Functional Partners:
T45_03379
Major Facilitator Superfamily protein.
 
     0.800
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
       0.762
gltB_1
Glutamate synthase [NADPH] large chain.
    
 
 0.703
fkbP_2
FK506-binding protein.
       0.676
rbsR_9
Ribose operon repressor.
  
     0.625
dhbF_8
Dimodular nonribosomal peptide synthase.
    
 
 0.600
lgrD_2
Linear gramicidin synthase subunit D.
    
   0.597
T45_03374
Hypothetical protein.
       0.595
ptsH
Phosphocarrier protein HPr.
   
 
 0.577
pheT
phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
    
   0.522
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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