| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| T45_08247 | arc | T45_08247 | T45_03386 | Hypothetical protein. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.991 |
| T45_08247 | ftsH_1 | T45_08247 | T45_01398 | Hypothetical protein. | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | 0.991 |
| T45_08247 | glpK_1 | T45_08247 | T45_03403 | Hypothetical protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.973 |
| T45_08247 | prcA | T45_08247 | T45_03381 | Hypothetical protein. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.979 |
| T45_08247 | prcB | T45_08247 | T45_03382 | Hypothetical protein. | Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.979 |
| T45_08247 | yrrB | T45_08247 | T45_02246 | Hypothetical protein. | TPR repeat-containing protein YrrB. | 0.944 |
| arc | T45_08247 | T45_03386 | T45_08247 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Hypothetical protein. | 0.991 |
| arc | glpK_1 | T45_03386 | T45_03403 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.989 |
| arc | mec | T45_03386 | T45_04314 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | cysO-cysteine peptidase. | 0.991 |
| arc | prcA | T45_03386 | T45_03381 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.999 |
| arc | prcB | T45_03386 | T45_03382 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.999 |
| arc | wapA_7 | T45_03386 | T45_04491 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | tRNA nuclease WapA precursor. | 0.991 |
| arc | yrrB | T45_03386 | T45_02246 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | TPR repeat-containing protein YrrB. | 0.981 |
| ftsH_1 | T45_08247 | T45_01398 | T45_08247 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Hypothetical protein. | 0.991 |
| ftsH_1 | glpK_1 | T45_01398 | T45_03403 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.989 |
| ftsH_1 | mec | T45_01398 | T45_04314 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | cysO-cysteine peptidase. | 0.991 |
| ftsH_1 | prcA | T45_01398 | T45_03381 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.993 |
| ftsH_1 | prcB | T45_01398 | T45_03382 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.994 |
| ftsH_1 | wapA_7 | T45_01398 | T45_04491 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | tRNA nuclease WapA precursor. | 0.991 |
| ftsH_1 | yrrB | T45_01398 | T45_02246 | ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family. | TPR repeat-containing protein YrrB. | 0.981 |
STRING v12.5 is now available!
