Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_03423Phosphatidylinositol 3- and 4-kinase. (278 aa)    
Predicted Functional Partners:
T45_03424
Hypothetical protein.
 
    0.970
pspA_2
Phosphoserine phosphatase 1.
 
     0.935
T45_07336
Hypothetical protein.
    
 0.922
mshC
L-cysteine:1D-myo-inositol; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
     0.872
T45_03243
ATP-dependent helicase HepA.
   
 0.805
T45_04729
ATP-dependent helicase HepA.
   
 0.805
T45_07701
Hypothetical protein.
   
 0.805
serS
serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
    
   0.728
T45_00219
Translocation protein TolB.
    
 0.716
T45_00835
Translocation protein TolB.
    
 0.716
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (20%) [HD]