hmgA protein (Streptomyces turgidiscabies) - STRING interaction network

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hmgA

Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (452 aa)

Predicted Functional Partners:

hpd

0.997

T45_02355

0.983

fahA

0.977

lly

0.935

mce

0.879

T45_09059

0.848

yvoA_6

0.830

T45_03515

0.792

tetR_3

0.761

tfdF

0.692

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_02355	fahA	T45_02355	T45_07240	4-hydroxymandelate synthase.	Fumarylacetoacetate (FAA hydrolase family.	0.852
T45_02355	hmgA	T45_02355	T45_03513	4-hydroxymandelate synthase.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.983
T45_03515	hmgA	T45_03515	T45_03513	Hypothetical protein.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.792
T45_03515	tetR_3	T45_03515	T45_03512	Hypothetical protein.	Tetracycline repressor protein class G.	0.709
T45_03515	yvoA_6	T45_03515	T45_03514	Hypothetical protein.	HTH-type transcriptional repressor YvoA.	0.830
T45_09059	hmgA	T45_09059	T45_03513	Hypothetical protein.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.848
fahA	T45_02355	T45_07240	T45_02355	Fumarylacetoacetate (FAA hydrolase family.	4-hydroxymandelate synthase.	0.852
fahA	hmgA	T45_07240	T45_03513	Fumarylacetoacetate (FAA hydrolase family.	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	0.977
fahA	hpd	T45_07240	T45_04328	Fumarylacetoacetate (FAA hydrolase family.	4-hydroxyphenylpyruvate dioxygenase.	0.927
fahA	lly	T45_07240	T45_08832	Fumarylacetoacetate (FAA hydrolase family.	4-hydroxyphenylpyruvate dioxygenase.	0.545
hmgA	T45_02355	T45_03513	T45_02355	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	4-hydroxymandelate synthase.	0.983
hmgA	T45_03515	T45_03513	T45_03515	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Hypothetical protein.	0.792
hmgA	T45_09059	T45_03513	T45_09059	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Hypothetical protein.	0.848
hmgA	fahA	T45_03513	T45_07240	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Fumarylacetoacetate (FAA hydrolase family.	0.977
hmgA	hpd	T45_03513	T45_04328	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	4-hydroxyphenylpyruvate dioxygenase.	0.997
hmgA	lly	T45_03513	T45_08832	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	4-hydroxyphenylpyruvate dioxygenase.	0.935
hmgA	mce	T45_03513	T45_02052	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein.	0.879
hmgA	tetR_3	T45_03513	T45_03512	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Tetracycline repressor protein class G.	0.761
hmgA	tfdF	T45_03513	T45_04970	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	Maleylacetate reductase.	0.692
hmgA	yvoA_6	T45_03513	T45_03514	Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.	HTH-type transcriptional repressor YvoA.	0.830

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