Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sigK_3ECF RNA polymerase sigma factor SigK; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa)    
Predicted Functional Partners:
T45_03521
anti-sigma-K factor RskA.
 
 
 0.986
rskA
anti-sigma-K factor RskA.
 
 
 0.921
sigM_1
ECF RNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.759
T45_03523
Hypothetical protein.
 
 
   0.684
sigC_1
ECF RNA polymerase sigma factor SigC; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.656
rpoB_1
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.632
sigD_1
ECF RNA polymerase sigma factor SigD; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.627
sigW_2
ECF RNA polymerase sigma factor SigW; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.623
sigR
ECF RNA polymerase sigma factor SigR; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.609
sigE_12
RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.584
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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