Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
T45_03554Hypothetical protein. (632 aa)    
Predicted Functional Partners:
pcaB
3-carboxy-cis,cis-muconate cycloisomerase.
    
  0.803
ntaA_2
Nitrilotriacetate monooxygenase component A.
 
     0.693
ysnE
Putative N-acetyltransferase YsnE.
  
     0.668
T45_03552
Hypothetical protein.
 
     0.612
fliY
Cystine-binding periplasmic protein precursor.
 
     0.528
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
     
  0.499
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
  0.450
T45_03081
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthase.
     
  0.440
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
  0.440
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
     
  0.426
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: medium (52%) [HD]