stp_10 protein (Streptomyces turgidiscabies)

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Score

stp_10

Multidrug resistance protein stp. (493 aa)

Predicted Functional Partners:

T45_03637

0.794

ndkA

0.601

dut

0.600

dhbF_8

0.582

tmk

0.562

vioD

0.544

gltB_1

0.516

fruA

0.510

metH

0.502

nrdZ

0.498

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_03637	stp_10	T45_03637	T45_03638	Transcriptional regulator BetI.	Multidrug resistance protein stp.	0.794
T45_03637	vioD	T45_03637	T45_03639	Transcriptional regulator BetI.	Putative tryptophan hydroxylase VioD.	0.771
dhbF_8	fruA	T45_05484	T45_02389	Dimodular nonribosomal peptide synthase.	PTS system fructose-specific EIIABC component.	0.830
dhbF_8	gltB_1	T45_05484	T45_04042	Dimodular nonribosomal peptide synthase.	Glutamate synthase [NADPH] large chain.	0.948
dhbF_8	metH	T45_05484	T45_03400	Dimodular nonribosomal peptide synthase.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.830
dhbF_8	ndkA	T45_05484	T45_00600	Dimodular nonribosomal peptide synthase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.406
dhbF_8	stp_10	T45_05484	T45_03638	Dimodular nonribosomal peptide synthase.	Multidrug resistance protein stp.	0.582
dhbF_8	tmk	T45_05484	T45_00750	Dimodular nonribosomal peptide synthase.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.701
dhbF_8	vioD	T45_05484	T45_03639	Dimodular nonribosomal peptide synthase.	Putative tryptophan hydroxylase VioD.	0.648
dut	ndkA	T45_05454	T45_00600	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.974
dut	nrdZ	T45_05454	T45_01871	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Ribonucleoside-diphosphate reductase NrdZ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.853
dut	stp_10	T45_05454	T45_03638	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Multidrug resistance protein stp.	0.600
dut	tmk	T45_05454	T45_00750	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.933
fruA	dhbF_8	T45_02389	T45_05484	PTS system fructose-specific EIIABC component.	Dimodular nonribosomal peptide synthase.	0.830
fruA	gltB_1	T45_02389	T45_04042	PTS system fructose-specific EIIABC component.	Glutamate synthase [NADPH] large chain.	0.449
fruA	metH	T45_02389	T45_03400	PTS system fructose-specific EIIABC component.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.489
fruA	stp_10	T45_02389	T45_03638	PTS system fructose-specific EIIABC component.	Multidrug resistance protein stp.	0.510
fruA	tmk	T45_02389	T45_00750	PTS system fructose-specific EIIABC component.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.468
gltB_1	dhbF_8	T45_04042	T45_05484	Glutamate synthase [NADPH] large chain.	Dimodular nonribosomal peptide synthase.	0.948
gltB_1	fruA	T45_04042	T45_02389	Glutamate synthase [NADPH] large chain.	PTS system fructose-specific EIIABC component.	0.449