mec protein (Streptomyces turgidiscabies) - STRING interaction network

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[Homology]

Score

mec

cysO-cysteine peptidase. (140 aa)

Predicted Functional Partners:

cysO_1

0.978

cysM

0.933

cysO_2

0.929

moeZ

0.882

ftsH_1

0.856

arc

0.856

yrrB

0.843

pncB1

0.829

T45_04050

0.826

T45_07413

0.826

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_04050	arc	T45_04050	T45_03386	Ankyrin repeats (3 copies.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.734
T45_04050	ftsH_1	T45_04050	T45_01398	Ankyrin repeats (3 copies.	ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family.	0.734
T45_04050	mec	T45_04050	T45_04314	Ankyrin repeats (3 copies.	cysO-cysteine peptidase.	0.826
T45_04050	moeZ	T45_04050	T45_01814	Ankyrin repeats (3 copies.	Putative adenylyltransferase/sulfurtransferase.	0.565
T45_04050	pncB1	T45_04050	T45_04317	Ankyrin repeats (3 copies.	Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.428
T45_04050	yrrB	T45_04050	T45_02246	Ankyrin repeats (3 copies.	TPR repeat-containing protein YrrB.	0.956
T45_07413	arc	T45_07413	T45_03386	Putative lyase.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.734
T45_07413	ftsH_1	T45_07413	T45_01398	Putative lyase.	ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family.	0.734
T45_07413	mec	T45_07413	T45_04314	Putative lyase.	cysO-cysteine peptidase.	0.826
T45_07413	moeZ	T45_07413	T45_01814	Putative lyase.	Putative adenylyltransferase/sulfurtransferase.	0.565
T45_07413	pncB1	T45_07413	T45_04317	Putative lyase.	Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.428
T45_07413	yrrB	T45_07413	T45_02246	Putative lyase.	TPR repeat-containing protein YrrB.	0.937
arc	T45_04050	T45_03386	T45_04050	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	Ankyrin repeats (3 copies.	0.734
arc	T45_07413	T45_03386	T45_07413	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	Putative lyase.	0.734
arc	mec	T45_03386	T45_04314	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	cysO-cysteine peptidase.	0.856
arc	yrrB	T45_03386	T45_02246	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	TPR repeat-containing protein YrrB.	0.872
cysM	cysO_1	T45_04312	T45_04313	O-phosphoserine sulfhydrylase.	Sulfur carrier protein CysO.	0.974
cysM	cysO_2	T45_04312	T45_06115	O-phosphoserine sulfhydrylase.	Sulfur carrier protein CysO.	0.840
cysM	mec	T45_04312	T45_04314	O-phosphoserine sulfhydrylase.	cysO-cysteine peptidase.	0.933
cysM	pncB1	T45_04312	T45_04317	O-phosphoserine sulfhydrylase.	Nicotinate phosphoribosyltransferase pncB1; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.612