STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)    
Predicted Functional Partners:
stiP
Cysteine protease StiP precursor.
  
 0.999
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
 
 0.999
rpmA
50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.999
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.999
ndkA
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.999
T45_01271
Hypothetical protein.
  
 0.999
rpmH
50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
   
 
 0.999
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 0.999
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
  
 
 0.999
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
   
 
 0.999
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.