Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nlhH_4Carboxylesterase NlhH. (306 aa)    
Predicted Functional Partners:
dhbF_8
Dimodular nonribosomal peptide synthase.
  
 0.891
nlhH_3
Carboxylesterase NlhH.
  
     0.774
mlhB_2
Monoterpene epsilon-lactone hydrolase.
  
     0.773
mlhB_3
Monoterpene epsilon-lactone hydrolase.
  
     0.772
mlhB_4
Monoterpene epsilon-lactone hydrolase.
  
     0.771
mlhB_1
Monoterpene epsilon-lactone hydrolase.
  
     0.738
puuB_1
Gamma-glutamylputrescine oxidoreductase.
 
 
   0.708
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.695
nlhH_7
Carboxylesterase NlhH.
  
     0.683
nuoE
NADH-quinone oxidoreductase subunit E.
    
  0.609
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (14%) [HD]