Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
devR_4Transcriptional regulatory protein DevR (DosR). (831 aa)    
Predicted Functional Partners:
barA_2
Signal transduction histidine-protein kinase.
   
 0.988
luxQ
Autoinducer 2 sensor kinase/phosphatase LuxQ.
   
 0.959
T45_09072
Sensory histidine kinase AtoS.
  
 0.942
T45_04593
Hypothetical protein.
 
     0.827
rsbU_3
Phosphoserine phosphatase RsbU.
  
 0.805
T45_07062
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 0.805
T45_01411
Sensory histidine kinase AtoS.
   
 0.787
rsbP_1
Phosphoserine phosphatase RsbP.
   
 0.732
devS_1
Redox sensor histidine kinase response regulator.
 
 0.716
dosT
Hypoxia sensor histidine kinase response.
 
 0.713
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (12%) [HD]