Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hyiHydroxypyruvate isomerase; Belongs to the hyi family. (279 aa)    
Predicted Functional Partners:
garR_2
2-hydroxy-3-oxopropionate reductase.
 
 0.993
gcl
Glyoxylate carboligase; Belongs to the TPP enzyme family.
 
 
 0.976
ghrB_3
Glyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.882
T45_05634
D-amino acid dehydrogenase small subunit.
  
  
  0.875
garR_4
2-hydroxy-3-oxopropionate reductase.
 
 
 0.868
pucG
Purine catabolism protein PucG.
     
  0.772
garR_6
2-hydroxy-3-oxopropionate reductase.
 
 0.756
uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
     0.749
garR_5
2-hydroxy-3-oxopropionate reductase.
 
 0.743
glxR
2-hydroxy-3-oxopropionate reductase.
 
 
 0.740
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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