Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uoxUricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (311 aa)    
Predicted Functional Partners:
hiuH
5-hydroxyisourate hydrolase precursor; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
 
 0.997
pucL
Uric acid degradation bifunctional protein PucL.
 
  
 0.986
allB
Allantoinase.
 
 
 0.930
T45_04693
8-oxoguanine deaminase.
 
  
 0.908
T45_01507
OHCU decarboxylase.
 
  
 0.887
cutS_3
Carbon monoxide dehydrogenase small chain.
  
 
 0.865
uacT
Uric acid transporter UacT.
 
  
 0.841
hcrB
4-hydroxybenzoyl-CoA reductase subunit beta.
    
 0.775
T45_05105
Hypothetical protein.
    
 0.775
T45_05106
Hypothetical protein.
    
 0.775
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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