Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
T45_046938-oxoguanine deaminase. (457 aa)    
Predicted Functional Partners:
hiuH
5-hydroxyisourate hydrolase precursor; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.935
pucL
Uric acid degradation bifunctional protein PucL.
 
     0.912
uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.908
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
  0.790
T45_04689
Hypothetical protein.
 
     0.759
mtnP
S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
    
 0.736
speE_1
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.726
yfiH
Laccase domain protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.726
T45_04688
Hypothetical protein.
       0.721
uacT
Uric acid transporter UacT.
 
  
 0.714
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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