Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
alaA_2Glutamate-pyruvate aminotransferase AlaA. (402 aa)    
Predicted Functional Partners:
gltB_1
Glutamate synthase [NADPH] large chain.
    
 0.903
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.825
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
   
 0.812
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.804
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.801
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.800
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 
 0.795
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
 0.793
maeA
NAD-dependent malic enzyme.
  
 0.793
gdhB_3
NAD-specific glutamate dehydrogenase.
     
 0.790
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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