Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
T45_04807Prolyl oligopeptidase family protein. (652 aa)    
Predicted Functional Partners:
dppA_3
D-aminopeptidase.
 
     0.881
dapE_4
Succinyl-diaminopimelate desuccinylase.
       0.851
ykfA
Putative murein peptide carboxypeptidase.
       0.793
T45_04809
Hypothetical protein.
       0.774
T45_04810
ribosomal-protein-S5-alanine.
       0.746
guaA_2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
  0.664
guaB_5
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.634
tam_2
Trans-aconitate 2-methyltransferase.
       0.625
guaB_4
Inosine-5'-monophosphate dehydrogenase.
     
  0.625
crr
Glucose-specific phosphotransferase enzyme IIA.
    
   0.604
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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