Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nedA_2Sialidase precursor. (636 aa)    
Predicted Functional Partners:
exo
Beta-hexosaminidase.
 
 0.912
strH
beta-N-acetylhexosaminidase precursor.
 
 0.906
T45_05033
beta-N-acetylhexosaminidase.
 
 0.905
agaA_3
Alpha-galactosidase A precursor.
  
  
  0.869
chiA2_1
Chitinase precursor.
     
  0.838
nedA_3
Sialidase precursor.
 
  
 
0.819
nedA_1
Sialidase precursor.
 
  
 
0.817
agaA_4
Alpha-galactosidase A precursor.
     
  0.772
lacZ_1
Beta-galactosidase.
 
  
 0.768
rafA_1
Alpha-galactosidase.
     
  0.768
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
Server load: low (22%) [HD]