fpg2 protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

fpg2

Putative formamidopyrimidine-DNA; Belongs to the FPG family. (294 aa)

Predicted Functional Partners:

polA_1

0.934

fpg1

0.928

rsbP_5

0.876

nei1

0.868

T45_05044

0.721

ypcP

0.680

coaE

0.662

T45_09113

0.647

nei

0.625

uvrC

0.602

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T45_05044	fpg2	T45_05044	T45_05047	Hypothetical protein.	Putative formamidopyrimidine-DNA; Belongs to the FPG family.	0.721
T45_05044	rsbP_5	T45_05044	T45_05046	Hypothetical protein.	Phosphoserine phosphatase RsbP.	0.724
T45_09113	coaE	T45_09113	T45_04082	HhH-GPD superfamily base excision DNA repair protein.	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.416
T45_09113	fpg1	T45_09113	T45_05798	HhH-GPD superfamily base excision DNA repair protein.	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.454
T45_09113	fpg2	T45_09113	T45_05047	HhH-GPD superfamily base excision DNA repair protein.	Putative formamidopyrimidine-DNA; Belongs to the FPG family.	0.647
T45_09113	nei	T45_09113	T45_05338	HhH-GPD superfamily base excision DNA repair protein.	Endonuclease 8.	0.454
T45_09113	nei1	T45_09113	T45_00615	HhH-GPD superfamily base excision DNA repair protein.	Endonuclease 8 1; Belongs to the FPG family.	0.454
T45_09113	polA_1	T45_09113	T45_04072	HhH-GPD superfamily base excision DNA repair protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.661
T45_09113	ypcP	T45_09113	T45_03354	HhH-GPD superfamily base excision DNA repair protein.	5'-3' exonuclease.	0.614
coaE	T45_09113	T45_04082	T45_09113	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	HhH-GPD superfamily base excision DNA repair protein.	0.416
coaE	fpg1	T45_04082	T45_05798	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	0.848
coaE	fpg2	T45_04082	T45_05047	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Putative formamidopyrimidine-DNA; Belongs to the FPG family.	0.662
coaE	nei	T45_04082	T45_05338	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Endonuclease 8.	0.662
coaE	nei1	T45_04082	T45_00615	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Endonuclease 8 1; Belongs to the FPG family.	0.662
coaE	polA_1	T45_04082	T45_04072	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.764
fpg1	T45_09113	T45_05798	T45_09113	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	HhH-GPD superfamily base excision DNA repair protein.	0.454
fpg1	coaE	T45_05798	T45_04082	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.848
fpg1	fpg2	T45_05798	T45_05047	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	Putative formamidopyrimidine-DNA; Belongs to the FPG family.	0.928
fpg1	nei1	T45_05798	T45_00615	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	Endonuclease 8 1; Belongs to the FPG family.	0.902
fpg1	polA_1	T45_05798	T45_04072	formamidopyrimidine-DNA glycosylase 1; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.939