Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
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[Homology]
Score
frdBFumarate reductase iron-sulfur subunit. (249 aa)    
Predicted Functional Partners:
T45_05062
Succinate dehydrogenase/Fumarate reductase.
 
 0.999
frdA
Fumarate reductase flavoprotein subunit.
 
 0.999
sdhC
Succinate dehydrogenase/Fumarate reductase.
  
 0.994
T45_01505
Succinate dehydrogenase cytochrome b556 small.
  
 0.993
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
 
 0.985
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.984
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.972
sdhA_1
Succinate dehydrogenase flavoprotein subunit.
  
 0.967
sdhA_2
Succinate dehydrogenase flavoprotein subunit.
  
 0.967
sucD_1
succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.967
Your Current Organism:
Streptomyces turgidiscabies
NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113
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