| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARR49837.1 | trmL | CAY62_09805 | CAY62_13360 | TRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.444 |
| ARR50404.1 | ARR50405.1 | CAY62_13350 | CAY62_13355 | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| ARR50404.1 | cpxP | CAY62_13350 | CAY62_13345 | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.531 |
| ARR50404.1 | trmL | CAY62_13350 | CAY62_13360 | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.563 |
| ARR50405.1 | ARR50404.1 | CAY62_13355 | CAY62_13350 | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| ARR50405.1 | cpxP | CAY62_13355 | CAY62_13345 | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| ARR50405.1 | trmL | CAY62_13355 | CAY62_13360 | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.588 |
| ARR51077.1 | trmL | CAY62_16565 | CAY62_13360 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.452 |
| cpxP | ARR50404.1 | CAY62_13345 | CAY62_13350 | Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.531 |
| cpxP | ARR50405.1 | CAY62_13345 | CAY62_13355 | Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
| cpxP | trmL | CAY62_13345 | CAY62_13360 | Stress adaptor protein CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.438 |
| hemF | trmL | CAY62_14485 | CAY62_13360 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.647 |
| rlmH | trmB | CAY62_10680 | CAY62_11940 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | tRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.417 |
| rlmH | trmL | CAY62_10680 | CAY62_13360 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.408 |
| trmB | rlmH | CAY62_11940 | CAY62_10680 | tRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.417 |
| trmB | trmL | CAY62_11940 | CAY62_13360 | tRNA (guanosine(46)-N7)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.448 |
| trmL | ARR49837.1 | CAY62_13360 | CAY62_09805 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | TRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| trmL | ARR50404.1 | CAY62_13360 | CAY62_13350 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
| trmL | ARR50405.1 | CAY62_13360 | CAY62_13355 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | Two-component system sensor histidine kinase CpxA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.588 |
| trmL | ARR51077.1 | CAY62_13360 | CAY62_16565 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.452 |