STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroK-2Transcriptional regulator, XRE family with shikimate kinase activity; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (310 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
 0.944
ACR02491.1
TIGRFAM: benzoyl-CoA-dihydrodiol lyase; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: azo:azo3056 enoyl-CoA hydratase.
 
   
 0.793
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
  
 0.792
ACR02492.1
TIGRFAM: benzoyl-CoA oxygenase, B subunit; KEGG: eba:ebA2765 benzoyl-CoA oxygenase component B.
 
     0.787
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.750
ACR01733.1
TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: azo:azo3052 benzoate-coa ligase.
 
  
 0.744
ACR01637.1
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: azo:azo1068 chorismate mutase/prephenate dehydratase.
  
  
 0.731
ACR01443.1
KEGG: mpt:Mpe_A2628 chorismate binding enzyme; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; aminotransferase class IV.
 
  
 0.619
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
   
 0.613
ACR01732.1
PFAM: Extracellular ligand-binding receptor; KEGG: azo:azo3050 putative leucine-specific binding protein.
 
    0.591
Your Current Organism:
Thauera sp. MZ1T
NCBI taxonomy Id: 85643
Other names: T. sp. MZ1T
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