| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MICA_154 | cysS | MICA_154 | MICA_155 | Response regulator. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.563 |
| MICA_154 | pyrC | MICA_154 | MICA_153 | Response regulator. | Dihydroorotase, multifunctional complex type domain protein. | 0.544 |
| MICA_176 | carA | MICA_176 | MICA_1587 | Oxidoreductase FAD-binding domain protein. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.919 |
| MICA_176 | carB | MICA_176 | MICA_1589 | Oxidoreductase FAD-binding domain protein. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.943 |
| MICA_176 | guaA | MICA_176 | MICA_2282 | Oxidoreductase FAD-binding domain protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.589 |
| MICA_176 | pyrB | MICA_176 | MICA_1941 | Oxidoreductase FAD-binding domain protein. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.934 |
| MICA_176 | pyrC | MICA_176 | MICA_153 | Oxidoreductase FAD-binding domain protein. | Dihydroorotase, multifunctional complex type domain protein. | 0.897 |
| MICA_176 | pyrD | MICA_176 | MICA_741 | Oxidoreductase FAD-binding domain protein. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.988 |
| MICA_176 | pyrE | MICA_176 | MICA_1853 | Oxidoreductase FAD-binding domain protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.936 |
| MICA_176 | pyrF | MICA_176 | MICA_142 | Oxidoreductase FAD-binding domain protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.930 |
| carA | MICA_176 | MICA_1587 | MICA_176 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Oxidoreductase FAD-binding domain protein. | 0.919 |
| carA | carB | MICA_1587 | MICA_1589 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
| carA | guaA | MICA_1587 | MICA_2282 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.596 |
| carA | pyrB | MICA_1587 | MICA_1941 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | MICA_1587 | MICA_153 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type domain protein. | 0.994 |
| carA | pyrD | MICA_1587 | MICA_741 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.945 |
| carA | pyrE | MICA_1587 | MICA_1853 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.929 |
| carA | pyrF | MICA_1587 | MICA_142 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.926 |
| carB | MICA_176 | MICA_1589 | MICA_176 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Oxidoreductase FAD-binding domain protein. | 0.943 |
| carB | carA | MICA_1589 | MICA_1587 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |