| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MICA_1737 | MICA_1980 | MICA_1737 | MICA_1980 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 0.677 |
| MICA_1737 | ispD | MICA_1737 | MICA_1285 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.568 |
| MICA_1737 | ubiA | MICA_1737 | MICA_262 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.933 |
| MICA_1737 | ubiE | MICA_1737 | MICA_916 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.533 |
| MICA_1860 | MICA_2417 | MICA_1860 | MICA_2417 | Glutaredoxin family protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 0.475 |
| MICA_1860 | ubiA | MICA_1860 | MICA_262 | Glutaredoxin family protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.910 |
| MICA_1980 | MICA_1737 | MICA_1980 | MICA_1737 | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | 0.677 |
| MICA_1980 | MICA_2417 | MICA_1980 | MICA_2417 | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 0.476 |
| MICA_1980 | ispD | MICA_1980 | MICA_1285 | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.607 |
| MICA_1980 | ubiA | MICA_1980 | MICA_262 | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.743 |
| MICA_1980 | ubiG | MICA_1980 | MICA_1436 | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.545 |
| MICA_2417 | MICA_1860 | MICA_2417 | MICA_1860 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Glutaredoxin family protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.475 |
| MICA_2417 | MICA_1980 | MICA_2417 | MICA_1980 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Electron transfer flavo-ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone. | 0.476 |
| MICA_2417 | ispD | MICA_2417 | MICA_1285 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.481 |
| MICA_2417 | ubiA | MICA_2417 | MICA_262 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.654 |
| MICA_2417 | ubiE | MICA_2417 | MICA_916 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.945 |
| MICA_2417 | ubiG | MICA_2417 | MICA_1436 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.984 |
| MICA_260 | MICA_261 | MICA_260 | MICA_261 | RNA methyltransferase family protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Hypothetical protein. | 0.450 |
| MICA_260 | ubiA | MICA_260 | MICA_262 | RNA methyltransferase family protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.648 |
| MICA_261 | MICA_260 | MICA_261 | MICA_260 | Hypothetical protein. | RNA methyltransferase family protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.450 |