Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)    
Predicted Functional Partners:
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.991
MICA_817
maeB.
  
 0.991
MICA_868
2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family.
  
 0.991
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.989
MICA_351
Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.976
MICA_1242
Hypothetical protein; Belongs to the PEPCase type 1 family.
     
 0.944
MICA_1604
Aminotransferase class I and II family protein.
  
 0.928
MICA_235
Beta-eliminating lyase family protein.
  
 0.928
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.924
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.902
Your Current Organism:
Micavibrio aeruginosavorus ARL13
NCBI taxonomy Id: 856793
Other names: M. aeruginosavorus ARL-13, Micavibrio aeruginosavorus ARL-13, Micavibrio aeruginosavorus str. ARL-13, Micavibrio aeruginosavorus strain ARL-13
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