Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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sucCsuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (400 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
sdhC
Succinate dehydrogenase, cytochrome b556 subunit.
  
 
 0.992
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein.
  
 
 0.990
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 0.990
sdhA
Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.989
MICA_1919
Succinate dehydrogenase and fumarate reductase iron-sulfur family protein.
  
 0.987
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.976
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.948
MICA_351
Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.943
MICA_1304
Transketolase, C-terminal domain protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.927
Your Current Organism:
Micavibrio aeruginosavorus ARL13
NCBI taxonomy Id: 856793
Other names: M. aeruginosavorus ARL-13, Micavibrio aeruginosavorus ARL-13, Micavibrio aeruginosavorus str. ARL-13, Micavibrio aeruginosavorus strain ARL-13
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