| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MICA_164 | ubiE | MICA_164 | MICA_916 | Sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.770 |
| MICA_1657 | MICA_2417 | MICA_1657 | MICA_2417 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 0.915 |
| MICA_1657 | ubiA | MICA_1657 | MICA_262 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.485 |
| MICA_1657 | ubiE | MICA_1657 | MICA_916 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.935 |
| MICA_1657 | ubiG | MICA_1657 | MICA_1436 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.982 |
| MICA_1737 | ubiA | MICA_1737 | MICA_262 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.933 |
| MICA_1737 | ubiE | MICA_1737 | MICA_916 | Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.533 |
| MICA_2417 | MICA_1657 | MICA_2417 | MICA_1657 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 0.915 |
| MICA_2417 | ubiA | MICA_2417 | MICA_262 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.654 |
| MICA_2417 | ubiE | MICA_2417 | MICA_916 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.945 |
| MICA_2417 | ubiG | MICA_2417 | MICA_1436 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.984 |
| MICA_917 | mviN | MICA_917 | MICA_918 | Hypothetical protein. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.519 |
| MICA_917 | trpS | MICA_917 | MICA_919 | Hypothetical protein. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.519 |
| MICA_917 | ubiE | MICA_917 | MICA_916 | Hypothetical protein. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.773 |
| lipA | ubiE | MICA_1289 | MICA_916 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.526 |
| mviN | MICA_917 | MICA_918 | MICA_917 | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | Hypothetical protein. | 0.519 |
| mviN | trpS | MICA_918 | MICA_919 | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.822 |
| mviN | ubiE | MICA_918 | MICA_916 | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | Ubiquinone/menaquinone biosynthesis methyltransferases family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.519 |
| trpS | MICA_917 | MICA_919 | MICA_917 | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | Hypothetical protein. | 0.519 |
| trpS | mviN | MICA_919 | MICA_918 | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.822 |