| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MICA_1018 | MICA_989 | MICA_1018 | MICA_989 | Formyl transferase, C-terminal domain protein. | nusB family protein. | 0.795 |
| MICA_1018 | folD | MICA_1018 | MICA_1821 | Formyl transferase, C-terminal domain protein. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.754 |
| MICA_989 | MICA_1018 | MICA_989 | MICA_1018 | nusB family protein. | Formyl transferase, C-terminal domain protein. | 0.795 |
| MICA_989 | fmt | MICA_989 | MICA_2405 | nusB family protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.795 |
| MICA_989 | folD | MICA_989 | MICA_1821 | nusB family protein. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.783 |
| MICA_989 | glyA | MICA_989 | MICA_987 | nusB family protein. | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.757 |
| MICA_989 | nrdR | MICA_989 | MICA_988 | nusB family protein. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.824 |
| MICA_989 | nusA | MICA_989 | MICA_1114 | nusB family protein. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.898 |
| MICA_989 | nusG | MICA_989 | MICA_2155 | nusB family protein. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.802 |
| MICA_989 | rpoZ | MICA_989 | MICA_2261 | nusB family protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.835 |
| MICA_989 | rpsJ | MICA_989 | MICA_2135 | nusB family protein. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.895 |
| MICA_989 | truB | MICA_989 | MICA_1110 | nusB family protein. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.782 |
| fmt | MICA_989 | MICA_2405 | MICA_989 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | nusB family protein. | 0.795 |
| fmt | folD | MICA_2405 | MICA_1821 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.735 |
| folD | MICA_1018 | MICA_1821 | MICA_1018 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Formyl transferase, C-terminal domain protein. | 0.754 |
| folD | MICA_989 | MICA_1821 | MICA_989 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | nusB family protein. | 0.783 |
| folD | fmt | MICA_1821 | MICA_2405 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.735 |
| folD | glyA | MICA_1821 | MICA_987 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.986 |
| glyA | MICA_989 | MICA_987 | MICA_989 | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | nusB family protein. | 0.757 |
| glyA | folD | MICA_987 | MICA_1821 | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.986 |