| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MICA_1605 | MICA_99 | MICA_1605 | MICA_99 | Prephenate dehydratase family protein. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.756 |
| MICA_1605 | aroA | MICA_1605 | MICA_151 | Prephenate dehydratase family protein. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.482 |
| MICA_2008 | MICA_99 | MICA_2008 | MICA_99 | Hypothetical protein. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.641 |
| MICA_240 | MICA_99 | MICA_240 | MICA_99 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.810 |
| MICA_240 | glyA | MICA_240 | MICA_987 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.405 |
| MICA_240 | thrC | MICA_240 | MICA_2290 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. | Threonine synthase. | 0.481 |
| MICA_911 | MICA_99 | MICA_911 | MICA_99 | Putative cysteine synthase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.911 |
| MICA_911 | cysK | MICA_911 | MICA_1618 | Putative cysteine synthase. | Cysteine synthase A. | 0.917 |
| MICA_99 | MICA_1605 | MICA_99 | MICA_1605 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Prephenate dehydratase family protein. | 0.756 |
| MICA_99 | MICA_2008 | MICA_99 | MICA_2008 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Hypothetical protein. | 0.641 |
| MICA_99 | MICA_240 | MICA_99 | MICA_240 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein. | 0.810 |
| MICA_99 | MICA_911 | MICA_99 | MICA_911 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Putative cysteine synthase. | 0.911 |
| MICA_99 | aroA | MICA_99 | MICA_151 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.724 |
| MICA_99 | cysK | MICA_99 | MICA_1618 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Cysteine synthase A. | 0.911 |
| MICA_99 | glyA | MICA_99 | MICA_987 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine hydroxymethyltransferase family protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.706 |
| MICA_99 | serA | MICA_99 | MICA_100 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.999 |
| MICA_99 | serB | MICA_99 | MICA_97 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Phosphoserine phosphatase SerB. | 0.977 |
| MICA_99 | thrC | MICA_99 | MICA_2290 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Threonine synthase. | 0.946 |
| aroA | MICA_1605 | MICA_151 | MICA_1605 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydratase family protein. | 0.482 |
| aroA | MICA_99 | MICA_151 | MICA_99 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.724 |